礼来28.8亿美元收购Merida布局自身免疫领域
Lilly to Buy Merida for $2.88 Billion in Autoimmune Push
关注礼来在核心业务护城河稳固期的战略扩张路径,其高频小额收购早期资产的模式对生物科技投资有参考意义。
Lilly has been making a bet on this particular space on immunology products for the last several years. It does have a number of products here as well, but the bigger story is that Lily is looking to actually put some of this power that is getting from selling diabetes shots and weight loss shots that have become so ubiquitous in the United States and the rest of the world. They're trying to put that to use so that when they do eventually lose some of that protection, some of that patent protection, they'll be able to, you know, have future income streams.
过去几年里,礼来(Lilly)一直在免疫学产品这一特定领域下注。它在此确实拥有不少产品,但更大的故事在于,礼来正试图将销售糖尿病注射剂和减肥针剂所获得的巨大收益——这些产品在美国及全球其他地区已变得无处不在——加以利用。他们希望借此在最终失去部分专利保护时,能够拥有未来的收入来源。
It's hard to look at now because they do make so much money from those. But immunology is a huge and growing area, and that's one of the areas where Lily is really staking its claim. Michelle, I go to the blue wipe Buyer Profile or intent profile page on the Bloomberg terminal, and Lily has made a number of acquisitions in recent weeks and months. Meredith is just the latest for $2.9 billion, but in August, there are two purchases up with some other companies into pro and amplification holdings in July.
现在很难去看待这一点,因为它们从这些产品中赚取了巨额利润。然而,免疫学是一个庞大且不断增长的领域,这也是礼来真正确立其地位的方向之一。米歇尔,我在彭博终端上查看蓝色擦拭买家画像或意图画像页面,礼来在过去几周和几个月里进行了多项收购。梅雷迪思是最新的一笔交易,金额为29亿美元,但在8月,有两笔收购公布,此外还有其他公司在7月进行了收购。
There is ratio therapeutics. Do any of these get the attention of regulators? You know these acquisitions don't aren't really getting the attention of regulators is getting a lot of attention from, um, from investors. Lilly is really taking a very different approach. They're buying things at a very early stage. It's a great question, actually. I don't know if they're if they're somehow, you know, covering up an awful lot of early stage products in the same category so that they could be kind of cornering the market on some new technology that's just emerging.
有比率疗法公司(Ratio Therapeutics)。这些收购是否会受到监管机构的关注?你知道这些收购并没有引起监管机构的太多关注,而是吸引了投资者的广泛关注。礼来采取了一种截然不同的方法。他们在非常早期的阶段进行收购。这其实是个很好的问题。我不确定他们是否在某种程度上掩盖了大量处于同一类别的早期产品,以便对某种新兴技术形成市场垄断。
It's so early what they're doing, though, I think that is probably unlikely and others would follow up quickly along. It's interesting all of those things that you're citing, the numbers. They've told us that they look at ten different acquisitions every single week, and so they're pulling the trigger a lot, but they're pulling it at a very low rate. Right. All of those ones that you're talking about, I think the biggest deal that Lilly has ever done is sub $8 billion.
不过,我认为由于他们所处的阶段非常早,这种情况可能不太可能发生,其他人也会迅速跟进。你提到的那些数字很有趣。他们告诉我们,每周都会审视十项不同的收购机会,因此他们频繁出手,但频率很低。没错。我认为你提到的所有交易中,礼来有史以来最大的一笔交易也低于80亿美元。
You know, like it is. It is comparatively to the size of the company. It's very small potatoes. They are just chucking a lot of potatoes. In all honesty, it's inching well. I've been in Bloomberg 17 years and I just learned another, uh, function today, the BP. Yeah, yeah. Very cool, I like that. Um, Michelle, uh, what does Eli Lilly prefer to do? They prefer to develop stuff in their lab or just go out and buy it. Like what?
你知道,就像它现在这样。与公司规模相比,这非常微不足道。他们只是撒下很多土豆。老实说,进展良好。我在彭博社工作了17年,今天又学到了另一个功能,BP。是的,是的。很酷,我喜欢这个。嗯,米歇尔,礼来公司更喜欢做什么?他们更喜欢在自己的实验室里开发东西还是直接出去购买?像什么?
This deal. All right, well, I mean, it's got to be a hard decision, right? Lilly paid the price of this a long time ago with Prozac. Of course, they were dominant in that particular space. And then when they lost the patent protection on Prozac, they really had to scramble. And then the GLP ones, they did that themselves like this is a huge market. Obviously they weren't first movers. That was Novo Nordisk. But but they developed their weight loss and obesity drugs in house, and they have really reaped the benefits there.
这笔交易。好吧,我的意思是,这肯定是一个艰难的决定,对吧?礼来很久以前就为这笔交易付出了代价,通过百忧解(Prozac)。当然,他们在该特定领域占据主导地位。然后当他们在百忧解上失去专利保护时,他们真的不得不匆忙应对。然后是GLP类药物,他们自己做了这件事,因为这是一个巨大的市场。显然他们不是先行者。那是诺和诺德。但他们开发了自家的减肥和肥胖药物,并从中真正获得了好处。
And they want to do that again. And the problem is, is that just can't be an expert everywhere. So they're bringing in stuff early stage. They're trying to develop it in house and then create it, you know, long term. We'll see what happens. A lot of other companies in this particular situation when they've had huge products that are losing mark a patent protection, they go out and do you know, 25 billion, 30,000,000,050.
他们想再次这样做。问题是,不可能在所有方面都是专家。所以他们早期引入一些东西。他们试图在内部开发它,然后长期创建它。我们看看会发生什么。许多其他公司在类似情况下,当他们拥有巨大产品且失去专利保护时,他们会出去进行250亿、3000万或5000万的交易。
I mean, not a lot because there's not a lot of companies that can only have that kind of money. But we do see massive M&A. They're doing massive numbers in terms of deals, not massive size of the deals themselves. I'm fascinated by the fact that, um, Eli Lilly is kind of scouring for deals, um, on such a frequent basis and yes, pulls the trigger on a couple of them, but, um, doesn't necessarily, uh, take a bite out of all of them.
我的意思是,不多,因为没有多少家公司能只拥有那种资金。但我们确实看到大规模的并购。他们在交易数量上做得很大,而不是交易规模本身很大。令我着迷的是,礼来公司如此频繁地搜寻交易机会,并且确实对其中几个采取了行动,但并不一定对所有交易都下手。
Um, what does that mean in terms of they're willing I mean, do they have like a goal of how many companies or investments they want to make. Um, you know, that they feel that they need to execute on. I don't think that they have a number that they need to execute on at this point. And to be fair, they don't have an awful lot of an awful lot of pressure at the moment. Right. The patterns that they have on these GLP one drugs, the shots, they have those for at least another decade.
嗯,这意味着他们在愿意方面是什么意思?我的意思是,他们是否有目标,比如想要投资多少家公司或投资项目?你知道,他们需要执行的那些。我认为他们目前没有一个需要执行的数字。公平地说,他们目前没有很大的压力。正确。他们在这些GLP-1药物上的模式,那些注射剂,他们至少还有十年的时间。
So that's not going to be hit too hard. And they are innovating in that particular space. Like we see some pills and whatnot that are coming along even more effective, more potent medicines. They will face a little bit of pressure because Novo Nordisk drugs are older and they are coming off patent. But Lilly's to this point have been a little bit more effective. So we'll see if that creates pressure. But it won't be, I think, for another, you know, 5 to 8 years that Lilly will actually start having to show how they're going to replace this medicine.
因此,这一领域受到的冲击不会太大。他们正在该特定领域进行创新。就像我们看到的一些药丸等,它们正带来更有效、效力更强的药物。它们会面临一定的压力,因为诺和诺德(Novo Nordisk)的药物上市时间较早且即将到期专利保护。但礼来(Lilly)的药物迄今为止效果略胜一筹。所以我们要看这是否会带来压力。但我认为,在5到8年内,礼来实际上还不需要展示他们将如何替代这种药物。
You only have to look at Pfizer and the struggles that they've had post-pandemic, right? When they've lost their Covid vaccines and their Covid treatments. They just do not want to do that.
你只需看看辉瑞(Pfizer)在后疫情时期所经历的困境,对吧?当他们失去了新冠疫苗和新冠治疗方法时。他们绝对不想重蹈覆辙。
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